Neurological conditions - multiple sclerosis

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Neurological conditions - multiple sclerosis

Improving health outcomes for people with multiple sclerosis through exercise

An older couple walking in a park

Exercise is crucial for self-management of multiple sclerosis (MS), improving quality of life (QoL) and health outcomes. People with multiple sclerosis (PwMS) are less physically active than the general population, with previous research being of insufficient quality to inform practice and failing to offer a practical solution that supports long-term participation.

Our research was the first pragmatic large-scale MS and exercise randomised control trial (RCT) in the world. Beneficiaries include people with MS, their families, exercise specialists and health professionals. The research has also impacted MS NICE guidelines, thereby shaping the practices of health and exercise professionals in the UK.

Funding partners


About this project

Explore the people, research centres and partner organisations behind this project.

Get in touch

Contact SPARC to discuss facilities, partnerships, doctoral research and more

Contact us

Publications

Carter, A. M., Daley, A. J., Kesterton, S. W., Woodroofe, N. M., Saxton, J. M., & Sharrack, B. (2013).Pragmatic exercise intervention in people with mild to moderate multiple sclerosis: a randomised controlled feasibility study. Contemporary Clinical Trials, 35(2), 40-47.

Saxton, J. M., Carter, A., Daley, A. J., Snowdon, N., Woodroofe, M. N., Petty, J., ... & Sharrack, B. (2013). Pragmatic exercise intervention for people with multiple sclerosis (ExIMS Trial): Study protocol for a randomised controlled trial. Contemporary clinical trials, 34(2), 205-211.

Carter, A., Daley, A., Humphreys, L., Snowdon, N., Woodroofe, N., Petty, J., ... & Saxton, J. M. (2014). Pragmatic intervention for increasing self-directed exercise behaviour and improving important health outcomes in people with multiple sclerosis: a randomised controlled trial. Multiple Sclerosis Journal, 20(8), 1112-1122.

Tosh, J., Dixon, S., Carter, A., Daley, A., Petty, J., Roalfe, A., ... & Saxton, J. M. (2014). Cost effectiveness of a pragmatic exercise intervention (EXIMS) for people with multiple sclerosis: economic evaluation of a randomised controlled trial. Multiple Sclerosis Journal, 20(8), 1123-1130.

Crank, H., Carter, A., Humphreys, L., Snowdon, N., Daley, A., Woodroofe, N., ... & Saxton, J. M. (2017). Qualitative investigation of exercise perceptions and experiences in people with multiple sclerosis before, during, and after participation in a personally tailored exercise program. Archives of physical medicine and rehabilitation, 98(12), 2520-2525.

Research team

Anouska Carter 123196

Dr Anouska Carter

Principal Researcher

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Liam Humphreys

Liam Humphreys

Research Fellow

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