Richard Gillis

Richard Gillis PhD

Lecturer in Food Science and Technology


Summary

I am an academic working in the field of macromolecules, their interactions, and how they impact the food we eat. I teach food technology, biotechnology and elements of food safety.

Teaching

Department of Service Sector Management

College of Business, Technology and Engineering

Subject Area

Food and Nutrition subject group

Publications

Journal articles

Abu Hammad, K., Dinu, V., MacCalman, T.E., Pattem, J., Goodall, M., Gillis, R.B., ... Harding, S.E. (2023). Comparative sedimentation equilibrium analysis of two IgG1 glycoforms: IgGCri and IgGWid. European biophysics journal : EBJ, 52 (4-5), 439-443. http://doi.org/10.1007/s00249-023-01656-x

Jacob, P.L., Brugnoli, B., Del Giudice, A., Phan, H., Chauhan, V.M., Beckett, L., ... Taresco, V. (2023). Poly (diglycerol adipate) variants as enhanced nanocarrier replacements in drug delivery applications. Journal of colloid and interface science, 641, 1043-1057. http://doi.org/10.1016/j.jcis.2023.03.124

Chun, T., Pattem, J., Gillis, R., Dinu, V.T., Yakubov, G.E., Corfield, A.P., & Harding, S.E. (2023). Comparative hydrodynamic and nanoscale imaging study on the interactions of teicoplanin-A2 and bovine submaxillary mucin as a model ocular mucin. Scientific Reports, 13 (1). http://doi.org/10.1038/s41598-023-38036-6

Apolinário, P.P., Zanchetta, F.C., Breder, J.S.C., Adams, G., Consonni, S.R., Gillis, R., ... Lima, M.H.M. (2023). Anti-inflammatory, procollagen, and wound repair properties of topical insulin gel. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 56. http://doi.org/10.1590/1414-431x2023e12640

Chun, T., Pattem, J., Gillis, R.B., Dinu, V.T., Yakubov, G.E., Corfield, A.P., & Harding, S.E. (2023). Self-association of the glycopeptide antibiotic teicoplanin A2 in aqueous solution studied by molecular hydrodynamics. Scientific Reports, 13 (1). http://doi.org/10.1038/s41598-023-28740-8

Alzahrani, Q.E., Gillis, R., Harding, S.E., Pinto, L.H., Gulati, M., Kapoor, B., ... Adams, G.G. (2022). Potential of the triad of fatty acids, polyphenols, and prebiotics from cucurbita against COVID-19 in diabetic patients: a review. Journal of Reports in Pharmaceutical Sciences, 11 (1), 28-40. http://doi.org/10.4103/jrptps.JRPTPS_144_21

Gillis, R.B., Solomon, H.V., Govada, L., Oldham, N.J., Dinu, V., Jiwani, S.I., ... Adams, G.G. (2021). Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques. Scientific reports, 11. http://doi.org/10.1038/s41598-021-81251-2

Wakefield, J.M.K., Hampe, R., Gillis, R.B., Sitterli, A., Adams, G.G., Kutzke, H., ... Harding, S.E. (2020). Aminoethyl substitution enhances the self-assembly properties of an aminocellulose as a potential archaeological wood consolidant. European Biophysics Journal, 49, 791-798. http://doi.org/10.1007/s00249-020-01451-y

Jiwani, S.I., Gillis, R.B., Besong, D., Almutairi, F., Erten, T., Kök, M.S., ... Adams, G.G. (2020). Isolation and Biophysical Characterisation of Bioactive Polysaccharides from Cucurbita Moschata (Butternut Squash). Polymers, 12 (8). http://doi.org/10.3390/polym12081650

Beji, O., Gillis, R.B., Dinu, V., Jiwani, S.I., Gyasi-Antwi, P., Fisk, I.D., ... Huang, S. (2020). Exploration of temperature and shelf-life dependency of the therapeutically available Insulin Detemir. European Journal of Pharmaceutics and Biopharmaceutics, 152, 340-347. http://doi.org/10.1016/j.ejpb.2020.05.016

Jiwani, S.I., Huang, S., Beji, O., Gyasi-Antwi, P., Gillis, R.B., & Adams, G.G. (2020). Clinically Relevant Insulin Degludec and its Interaction with Polysaccharides: A Biophysical Examination. Polymers, 12 (2). http://doi.org/10.3390/polym12020390

Dinu, V., Gadon, A., Hurst, K., Lim, M., Ayed, C., Gillis, R.B., ... Fisk, I.D. (2019). An enzymatically controlled mucoadhesive system for enhancing flavour during food oral processing. npj Science of Food, 3 (1), 1-8.

Dinu, V., Gillis, R., MacCalman, T., Lim, M., Adams, G.G., Harding, S.E., & Fisk, I.D. (2019). Submaxillary mucin: its effect on aroma release from acidic drinks and new insight into the effect of aroma compounds on its macromolecular integrity. Food Biophysics, 14 (3), 278-286. http://doi.org/10.1007/s11483-019-09574-2

Li, Y., Govada, L., Solomon, H., Gillis, R., Adams, G., & Chayen, N. (2019). Analysis of Glulisine Crystallisation Utilising Phase Diagrams and Nucleants. Crystals, 9 (9). http://doi.org/10.3390/cryst9090462

Dinu, V., Gadon, A., Hurst, K., Lim, M., Ayed, C., Gillis, R.B., ... Fisk, I.D. (2019). An enzymatically controlled mucoadhesive system for enhancing flavour during food oral processing. NPJ science of food, 3 (1). http://doi.org/10.1038/s41538-019-0043-y

Hartill, E., Gillis, R.B., Jiwani, S.I., Recchia, N., Meal, A., & Adams, G.G. (2018). Hypoglycaemic unawareness: A systematic review of qualitative studies of significant others'(SO) supportive interventions for patients with diabetes mellitus. Heliyon, 4 (10). http://doi.org/10.1016/j.heliyon.2018.e00887

Wakefield, J.M.K., Gillis, R.B., Adams, G.G., McQueen, C., & Harding, S.E. (2018). Controlled depolymerisation assessed by analytical ultracentrifugation of low molecular weight chitosan for use in archaeological conservation. European Biophysics Journal, 47, 769-775. http://doi.org/10.1007/s00249-018-1290-6

Channell, G.A., Adams, G.G., Lu, Y., Gillis, R.B., Dinu, V., Grundy, M.M.-.L., ... Harding, S.E. (2018). Use of the Extended Fujita method for representing the molecular weight and molecular weight distributions of native and processed oat beta-glucans. Scientific Reports, 8. http://doi.org/10.1038/s41598-018-29997-0

Adiewere, P., Gillis, R.B., Jiwani, S.I., Meal, A., Shaw, I., & Adams, G.G. (2018). A systematic review and meta-analysis of patient education in preventing and reducing the incidence or recurrence of adult diabetes foot ulcers (DFU). Heliyon, 4 (5). http://doi.org/10.1016/j.heliyon.2018.e00614

Adams, G.G., Meal, A., Morgan, P.S., Alzahrani, Q.E., Zobel, H., Lithgo, R., ... Gillis, R.B. (2018). Characterisation of insulin analogues therapeutically available to patients. PloS one, 13 (3). http://doi.org/10.1371/journal.pone.0195010

Adams, G.G., Alzahrani, Q., Jiwani, S.I., Meal, A., Morgan, P.S., Coffey, F., ... Chayen, N. (2017). Glargine and degludec: Solution behaviour of higher dose synthetic insulins. Scientific reports, 7 (1), 1-11.

Phillips-Jones, M.K., Lithgo, R., Dinu, V., Gillis, R., Harding, J.E., Adams, G.G., & Harding, S.E. (2017). Full hydrodynamic reversibility of the weak dimerization of vancomycin and elucidation of its interaction with VanS monomers at clinical concentration. Scientific reports, 7 (1). http://doi.org/10.1038/s41598-017-12620-z

Adams, G.G., Alzahrani, Q., Jiwani, S.I., Meal, A., Morgan, P.S., Coffey, F., ... Gillis, R.B. (2017). Glargine and degludec: Solution behaviour of higher dose synthetic insulins. Scientific reports, 7 (1). http://doi.org/10.1038/s41598-017-06642-w

Gillis, R., Adams, G.G., Besong, D., Machová, E., Ebringerová, A., Rowe, A.J., ... Patel, T.R. (2017). Application of novel analytical ultracentrifuge analysis to solutions of fungal mannans. European Biophysics Journal, 46 (3), 235-245. http://doi.org/10.1007/s00249-016-1159-5

Kerrison, G., Gillis, R.B., Jiwani, S.I., Alzahrani, Q., Kok, S., Harding, S.E., ... Adams, G.G. (2017). The effectiveness of lifestyle adaptation for the prevention of prediabetes in adults: a systematic review. Journal of diabetes research, 2017. http://doi.org/10.1155/2017/8493145

Phillips-Jones, M.K., Channell, G., Kelsall, C.J., Hughes, C.S., Ashcroft, A.E., Patching, S.G., ... Harding, S.E. (2017). Hydrodynamics of the VanA-type VanS histidine kinase: an extended solution conformation and first evidence for interactions with vancomycin. Scientific Reports, 7 (1). http://doi.org/10.1038/srep46180

Gillis, R.B., Adams, G.G., Alzahrani, Q., & Harding, S.E. (2016). A novel analytical ultracentrifugation based approach to the low resolution structure of gum Arabic. Biopolymers, 105 (9), 618-625.

Varzakas, T., Alghamdi, A., Alghamdi, H., Linforth, R., Dinu, V., Besong, T.D., ... Connerton, I.F. (2016). The effect of thermal processing in oil on the macromolecular integrity and acrylamide formation from starch of three potato cultivars organically fertilized. Cogent Food & Agriculture, 2 (1), 1180950.

Harding, S.E., Gillis, R.B., & Adams, G.G. (2016). Assessing sedimentation equilibrium profiles in analytical ultracentrifugation experiments on macromolecules: from simple average molecular weight analysis to molecular weight distribution and interaction analysis. Biophysical Reviews, 8 (4), 299-308.

McHale, E., Braovac, S., Steindal, C.C., Gillis, R.B., Adams, G.G., Harding, S.E., ... Kutzke, H. (2016). Synthesis and characterisation of lignin-like oligomers as a bio-inspired consolidant for waterlogged archaeological wood. Pure and Applied Chemistry, 88 (10-11), 969-977.

Uluisik, S., Chapman, N.H., Smith, R., Poole, M., Adams, G., Gillis, R.B., ... Seymour, G.B. (2016). Corrigendum: Genetic improvement of tomato by targeted control of fruit softening. Nature biotechnology, 34 (10), 1072. http://doi.org/10.1038/nbt1016-1072d

Uluisik, S., Chapman, N.H., Smith, R., Poole, M., Adams, G., Gillis, R.B., ... Seymour, G.B. (2016). Genetic improvement of tomato by targeted control of fruit softening. Nature biotechnology, 34 (9), 950-952. http://doi.org/10.1038/nbt.3602

Harding, S.E., Adams, G.G., & Gillis, R.B. (2016). Molecular weight analysis of starches: which technique? Starch - Stärke, 68 (9-10), 846-853. http://doi.org/10.1002/star.201600042

Berwick, M.R., Slope, L.N., Smith, C.F., King, S.M., Newton, S.L., Gillis, R.B., ... Peacock, A.F.A. (2016). Location dependent coordination chemistry and MRI relaxivity, in de novo designed lanthanide coiled coils. Chemical science, 7 (3), 2207-2216. http://doi.org/10.1039/c5sc04101e

Sweeney, S.M., Bullen, G.A., Gillis, R.B., Adams, G.G., Rowe, A.J., Harding, S.E., ... Murphy, P.V. (2016). Coiled coil type neoglycoproteins presenting three lactose residues. Tetrahedron Letters, 57 (13), 1414-1417. http://doi.org/10.1016/j.tetlet.2016.02.005

Alzahrani, Q.E., Adams, G.G., Gillis, R.B., Besong, T.M.D., Kök, M.S., Fong, E., ... Harding, S.E. (2016). Matrix-free hydrodynamic study on the size distribution and conformation of three technical lignins from wood and non-wood. Holzforschung, 70 (2), 117-125. http://doi.org/10.1515/hf-2014-0318

Harding, S.E., Gillis, R.B., Almutairi, F., Erten, T., Kök, M.Ş., & Adams, G.G. (2015). Recent advances in the analysis of macromolecular interactions using the matrix-free method of sedimentation in the analytical ultracentrifuge. Biology, 4 (1), 237-250.

Harding, S.E., Adams, G.G., Almutairi, F., Alzahrani, Q., Erten, T., Kök, M.S., & Gillis, R.B. (2015). Ultracentrifuge Methods for the Analysis of Polysaccharides, Glycoconjugates, and Lignins. Methods in enzymology, 562, 391-439. http://doi.org/10.1016/bs.mie.2015.06.043

Gillis, R.B., Rowe, A.J., Adams, G.G., & Harding, S.E. (2014). A review of modern approaches to the hydrodynamic characterisation of polydisperse macromolecular systems in biotechnology. Biotechnology & genetic engineering reviews, 30 (1-2), 142-157. http://doi.org/10.1080/02648725.2014.994870

Schuck, P., Gillis, R.B., Besong, T.M.D., Almutairi, F., Adams, G.G., Rowe, A.J., & Harding, S.E. (2014). SEDFIT-MSTAR: molecular weight and molecular weight distribution analysis of polymers by sedimentation equilibrium in the ultracentrifuge. The Analyst, 139 (1), 79-92. http://doi.org/10.1039/c3an01507f

Nikolajski, M., Adams, G.G., Gillis, R.B., Besong, D.T., Rowe, A.J., Heinze, T., & Harding, S.E. (2014). Protein-like fully reversible tetramerisation and super-association of an aminocellulose. Scientific reports, 4, 3861. http://doi.org/10.1038/srep03861

Soshnikova, Y.M., Roman, S.G., Chebotareva, N.A., Baum, O.I., Obrezkova, M.V., Gillis, R.B., ... Lunin, V.V. (2013). Starch-modified magnetite nanoparticles for impregnation into cartilage. Journal of Nanoparticle Research, 15 (11). http://doi.org/10.1007/s11051-013-2092-5

Gillis, R.B., Adams, G.G., Heinze, T., Nikolajski, M., Harding, S.E., & Rowe, A.J. (2013). MultiSig: a new high-precision approach to the analysis of complex biomolecular systems. European biophysics journal : EBJ, 42 (10), 777-786. http://doi.org/10.1007/s00249-013-0924-y

Gillis, R.B., Adams, G.G., Wolf, B., Berry, M., Besong, T.M.D., Corfield, A., ... Harding, S.E. (2013). Molecular weight distribution analysis by ultracentrifugation: adaptation of a new approach for mucins. Carbohydrate polymers, 93 (1), 178-183. http://doi.org/10.1016/j.carbpol.2012.05.018

Kök, M.S., Gillis, R., Ang, S., Lafond, D., Tatham, A.S., Adams, G., & Harding, S.E. (2012). Can dietary fibre help provide safer food products for sufferers of gluten intolerance? A well-established biophysical probe may help towards providing an answer. BMC biophysics, 5, 10. http://doi.org/10.1186/2046-1682-5-10

Imran, S., Gillis, R.B., Kok, M.S., Harding, S.E., & Adams, G.G. (2012). Application and use of Inulin as a tool for therapeutic drug delivery. Biotechnology & genetic engineering reviews, 28, 33-45. http://doi.org/10.5661/bger-28-33

Conference papers

Sweeney, S., Bullen, G., Berwick, M., Gillis, R., Rowe, A., Adams, G., ... Murphy, P. (2015). Synthesis of trimeric coiled coils presenting lactose as glycoclusters. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 250.

Book chapters

Harding, S.E., Adams, G.G., Gillis, R.B., Almutairi, F.M., & Morris, G.A. (2016). Aspects of the analytical ultracentrifuge determination of the molar mass distribution of polysaccharides. In Analytical Ultracentrifugation. (pp. 375-386). Springer, Tokyo

Harding, S.E., Abdelhameed, A.S., Gillis, R.B., Morris, G.A., & Adams, G.G. (2015). Characterization of capsular polysaccharides and their glycoconjugates by hydrodynamic methods. In Carbohydrate-Based Vaccines. (pp. 211-227). Humana Press, New York, NY

Other publications

Gillis, R.B. (2015). Protein polysaccharide complexes: permanent/nonpermanent interactions between polysaccharides and polypeptides. University of Nottingham

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